A simple, efficient, precise and accurate spectroscopic method has been developed and validated for quantitative estimation of terizidone in bulk and pharmaceutical dosage form. Terizidone standard solution was scanned in the UV range (400-200 nm) in a 1 cm quartz cell in a double beam UV spectrophotometer. The max of terizidone was 273.0 nm. The method obeys beers law in the concentration range from 4-12 μg/ml. The correlation coefficient was found to be 0.9994 and regression of the curve was found y=0.651x + 0.0258 with excellent recovery 99-101%. Limit of detection and limit of quantitation were found to be 0.09714 mg/ml and 0.29437 mg/ml respectively. The method was validated for several parameters like accuracy, precision as per ICH guidelines. Value of % RSD and % recovery was found satisfactory, hence the proposed method is precise, accurate and economical hence can be routine analysis.
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